Ibuprofen

Ibuprofen is a monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(2-methylpropyl)phenyl group. It has a role as a non-steroidal anti-inflammatory drug, a nonnarcotic analgesic, a cyclooxygenase 2 inhibitor, a cyclooxygenase 1 inhibitor, an antipyretic, a xenobiotic, an environmental contaminant, a radical scavenger, a drug allergen and a geroprotector. It derives from a propionic acid. Ibuprofen is considered to be among the safest NSAIDs and is generally well tolerated but can, nevertheless, rarely cause clinically apparent and serious acute liver injury.

• Pure, stable, anhydrous, crystalline form
• Good control of impurity profile by handling chemical steps in-house
• PSD tailored to FDF needs
• Technical support available on request

IUPAC name: (2RS)-2-[4-(2-Methylpropyl)phenyl]propanoic acid
Trade name: Advil, Motrin, Nurofen,
Other name: isobutylphenylpropionic acid

USP43